PDBe 1os7

X-ray diffraction
2.5Å resolution

Crystal structure of TauD with iron, alpha-ketoglutarate and Taurine bound at pH 7.5

Released:

Function and Biology Details

Reaction catalysed:
Taurine + 2-oxoglutarate + O(2) = sulfite + aminoacetaldehyde + succinate + CO(2). 
Biochemical function:
Biological process:
Cellular component:
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-ketoglutarate-dependent taurine dioxygenase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 283 amino acids
Theoretical weight: 32.45 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P37610 (Residues: 1-283; Coverage: 100%)
Gene names: JW0360, b0368, ssiD, tauD, yaiG
Sequence domains: Taurine catabolism dioxygenase TauD, TfdA family
Structure domains: Clavaminate synthase-like

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P212121
Unit cell:
a: 92.594Å b: 118.855Å c: 118.832Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.225 0.224 0.278
Expression system: Escherichia coli