PDBe 1oo3

Solution NMR

P395S mutant of the p85 regulatory subunit of the N-terminal src homology 2 domain of PI3-Kinase

Released:

Function and Biology Details

Biological process:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphatidylinositol 3-kinase regulatory subunit alpha Chain: A
Molecule details ›
Chain: A
Length: 111 amino acids
Theoretical weight: 12.86 KDa
Source organism: Bos taurus
Expression system: Escherichia coli
UniProt:
  • Canonical: P23727 (Residues: 321-431; Coverage: 15%)
Gene name: PIK3R1
Sequence domains: SH2 domain
Structure domains: SHC Adaptor Protein

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry, simulated annealing
Expression system: Escherichia coli