PDBe 1og1

X-ray diffraction
2Å resolution

CRYSTAL STRUCTURE OF THE EUCARYOTIC MONO-ADP-RIBOSYLTRANSFERASE ART2.2 IN COMPLEX WITH TAD

Released:
Source organism: Rattus norvegicus

Function and Biology Details

Reactions catalysed:
NAD(+) + H(2)O = ADP-D-ribose + nicotinamide. 
NAD(+) + protein-L-arginine = nicotinamide + N(omega)-(ADP-D-ribosyl)- protein-L-arginine. 
Biological process:
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
T-cell ecto-ADP-ribosyltransferase 2 Chain: A
Molecule details ›
Chain: A
Length: 226 amino acids
Theoretical weight: 26.07 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P20974 (Residues: 21-246; Coverage: 89%)
Gene names: Art2b, Rt6-b
Sequence domains: NAD:arginine ADP-ribosyltransferase
Structure domains: Toxin ADP-ribosyltransferase; Chain A, domain 1

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: P3121
Unit cell:
a: 81.419Å b: 81.419Å c: 77.265Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.202 0.202 0.244
Expression system: Escherichia coli