PDBe 1oey

X-ray diffraction
2Å resolution

Heterodimer of p40phox and p67phox PB1 domains from human NADPH oxidase

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Neutrophil cytosol factor 2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 83 amino acids
Theoretical weight: 9.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Best match: P19878 (Residues: 350-429)
Gene names: NCF2, NOXA2, P67PHOX
Neutrophil cytosol factor 4 Chains: J, K, L, M
Molecule details ›
Chains: J, K, L, M
Length: 107 amino acids
Theoretical weight: 12.85 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Best match: Q15080 (Residues: 237-339)
Gene names: NCF4, SH3PXD4

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P64
Unit cell:
a: 151.422Å b: 151.422Å c: 68.317Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.212 0.21 0.252
Expression system: Escherichia coli