› 1o7k

X-ray diffraction
2Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146977 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neutrophil cytosol factor 1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 131 amino acids
Theoretical weight: 15.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P14598 (Residues: 1-123; Coverage: 32%)
Gene names: NCF1, NOXO2, SH3PXD1A
Sequence domains: PX domain
Structure domains: Phox-like domain

Ligands and Environments

1 bound ligand:
Ligand SO4 7 x SO4
1 modified residue:
Ligand MSE 15 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: I222
Unit cell:
a: 74.233Å b: 92.175Å c: 144.01Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.223 0.21 0.254
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

65 review citations

Membrane recognition by phospholipid-binding domains.
Lemmon MA. (2008)
64 more

10 mentions without citation

Activation and assembly of the NADPH oxidase: a structural perspective.
Groemping et al. (2005)
9 more