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Crystal structure of an ATP phosphoribosyltransferase

Source organism: Thermotoga maritima
Biochemical function: glycosyltransferase activity
Biological process: amino acid biosynthetic process
Cellular component: cytoplasm

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EC 2.4.2.17: ATP phosphoribosyltransferase

Reaction catalysed:
1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = ATP + 5-phospho-alpha-D-ribose 1-diphosphate
Systematic name:
1-(5-phospho-beta-D-ribosyl)-ATP:diphosphate phospho-alpha-D-ribosyl-transferase
Alternative Name(s):
  • Adenosine triphosphate phosphoribosyltransferase
  • Phosphoribosyl ATP synthetase
  • Phosphoribosyl ATP:pyrophosphate phosphoribosyltransferase
  • Phosphoribosyl-ATP diphosphorylase
  • Phosphoribosyl-ATP pyrophosphorylase
  • Phosphoribosyl-ATP:pyrophosphate-phosphoribosyl phosphotransferase
  • Phosphoribosyladenosine triphosphate pyrophosphorylase
  • Phosphoribosyladenosine triphosphate synthetase
  • Phosphoribosyladenosine triphosphate:pyrophosphate phosphoribosyltransferase

GO terms

Sequence family

Pfam Protein family (Pfam)
PF01634
Domain description: ATP phosphoribosyltransferase
Occurring in:
  1. ATP phosphoribosyltransferase
The deposited structure of PDB entry 1o64 contains 2 copies of Pfam domain PF01634 (ATP phosphoribosyltransferase) in ATP phosphoribosyltransferase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR013820
Domain description: ATP phosphoribosyltransferase, catalytic domain
Occurring in:
  1. ATP phosphoribosyltransferase
IPR024893
Domain description: ATP phosphoribosyltransferase HisG, short form
Occurring in:
  1. ATP phosphoribosyltransferase
IPR018198
Domain description: ATP phosphoribosyltransferase, conserved site
Occurring in:
  1. ATP phosphoribosyltransferase
IPR001348
Domain description: ATP phosphoribosyltransferase HisG
Occurring in:
  1. ATP phosphoribosyltransferase

Structure domain

CATH CATH domain
3.40.190.10
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: D-Maltodextrin-Binding Protein; domain 2
Homology: Periplasmic binding protein-like II
Occurring in:
  1. ATP phosphoribosyltransferase
The deposited structure of PDB entry 1o64 contains 4 copies of CATH domain 3.40.190.10 (D-Maltodextrin-Binding Protein; domain 2) in ATP phosphoribosyltransferase. Showing 2 copies in chain A.
SCOP SCOP annotation
53851
Class: Alpha and beta proteins (a/b)
Fold: Periplasmic binding protein-like II
Superfamily: Periplasmic binding protein-like II
Occurring in:
  1. ATP phosphoribosyltransferase
The deposited structure of PDB entry 1o64 contains 2 copies of SCOP domain 53851 (Phosphate binding protein-like) in ATP phosphoribosyltransferase. Showing 1 copy in chain A.

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