PDBe 1nxk

X-ray diffraction
2.7Å resolution

Function and Biology Details

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo 12-mer
Entry contents:
1 distinct polypeptide molecule
MAP kinase-activated protein kinase 2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 400 amino acids
Theoretical weight: 46.19 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P49137 (Residues: 1-400; Coverage: 100%)
Gene name: MAPKAPK2
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

2 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P63
Unit cell:
a: 160.202Å b: 160.202Å c: 133.481Å
α: 90° β: 90° γ: 120°
R R work R free
0.241 0.239 0.274
Expression system: Escherichia coli BL21(DE3)