PDBe 1nw1

X-ray diffraction
2.02Å resolution

Crystal Structure of Choline Kinase

Released:
Source organism: Caenorhabditis elegans

Function and Biology Details

Reactions catalysed:
ATP + choline = ADP + phosphocholine. 
ATP + ethanolamine = ADP + O-phosphoethanolamine. 
Biochemical function:
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Choline kinase A2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 429 amino acids
Theoretical weight: 49.3 KDa
Source organism: Caenorhabditis elegans
Expression system: Escherichia coli
UniProt:
  • Canonical: Q22942 (Residues: 1-429; Coverage: 100%)
Gene names: C52B9.1, cka-2
Sequence domains: Choline/ethanolamine kinase
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 5ID-B
Spacegroup: P21
Unit cell:
a: 55.372Å b: 102.141Å c: 85.369Å
α: 90° β: 90.66° γ: 90°
R-values:
R R work R free
0.209 0.209 0.231
Expression system: Escherichia coli