› › Structure analysis

The Complex Structure Of Checkpoint Kinase Chk1/UCN-01

X-ray diffraction
2Å resolution
PDB entry 1nvq coloured by chain, front view.
PDB entry 1nvq coloured by chain, side view.
PDB entry 1nvq coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Serine/threonine-protein kinase Chk1 and peptide
hide full assembly name
Multimeric state: hetero dimer
Accessible surface area: 13487.37 Å2
Buried surface area: 1759.33 Å2
Dissociation area: 340.29 Å2
Dissociation energy (ΔGdiss): 0.3 kcal/mol
Dissociation entropy (TΔSdiss): 4.93 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-127094

Macromolecules

Serine/threonine-protein kinase Chk1
Chain: A
Length: 289 amino acids
Theoretical weight: 33.04 KDa
Source organism: Homo sapiens
Expression system: unidentified baculovirus
UniProt:
  • Canonical: O14757 (Residues: 1-289; Coverage: 61%)
Gene names: CHEK1, CHK1
Pfam: Protein kinase domain
InterPro:
CATH:
SCOP: Protein kinases, catalytic subunit
Serine/threonine-protein kinase Chk1 in PDB entry 1nvq, assembly 1, front view.
Serine/threonine-protein kinase Chk1 in PDB entry 1nvq, assembly 1, side view.
Serine/threonine-protein kinase Chk1 in PDB entry 1nvq, assembly 1, top view.
Molecule details ›

Search similar proteins

Peptide ASVSA
Chain: B
Length: 5 amino acids
Theoretical weight: 433 Da
Source organism: Homo sapiens
Expression system: Not provided
Peptide ASVSA in PDB entry 1nvq, assembly 1, front view.
Peptide ASVSA in PDB entry 1nvq, assembly 1, side view.
Peptide ASVSA in PDB entry 1nvq, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links