PDBe 1nug

X-ray diffraction
2.4Å resolution

Role of Calcium Ions in the Activation and Activity of the Transglutaminase 3 Enzyme (2 calciums, 1 Mg, inactive form)

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein-glutamine gamma-glutamyltransferase E Chains: A, B
Molecule details ›
Chains: A, B
Length: 692 amino acids
Theoretical weight: 76.67 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q08188 (Residues: 2-693; Coverage: 100%)
Gene name: TGM3
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P1
Unit cell:
a: 57.51Å b: 66.81Å c: 116.53Å
α: 97.24° β: 90.28° γ: 98.36°
R-values:
R R work R free
0.194 0.194 0.248
Expression system: Spodoptera frugiperda