PDBe 1nud

X-ray diffraction
2.7Å resolution

Role of Calcium Ions in the Activation and Activity of the Transglutaminase 3 Enzyme (3 calciums, active form)

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein-glutamine gamma-glutamyltransferase E Chains: A, B
Molecule details ›
Chains: A, B
Length: 692 amino acids
Theoretical weight: 76.67 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q08188 (Residues: 2-693; Coverage: 100%)
Gene name: TGM3
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P21
Unit cell:
a: 57.54Å b: 115.37Å c: 121.39Å
α: 90° β: 92.66° γ: 90°
R-values:
R R work R free
0.199 0.199 0.265
Expression system: Spodoptera frugiperda