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Crystal structure of galactose mutarotase from Lactococcus lactis mutant E304Q complexed with galactose

Source organism: Lactococcus lactis
Biochemical function: carbohydrate binding
Biological process: galactose catabolic process via UDP-galactose
Cellular component: cytoplasm

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EC 5.1.3.3: Aldose 1-epimerase

Reaction catalysed:
Alpha-D-glucose = beta-D-glucose
Systematic name:
Aldose 1-epimerase
Alternative Name(s):
  • Aldose mutarotase
  • Mutarotase

GO terms

Sequence family

Pfam Protein family (Pfam)
PF01263
Domain description: Aldose 1-epimerase
Occurring in:
  1. Aldose 1-epimerase
The deposited structure of PDB entry 1ns0 contains 2 copies of Pfam domain PF01263 (Aldose 1-epimerase) in Aldose 1-epimerase. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR047215
Domain description: Galactose mutarotase-like
Occurring in:
  1. Aldose 1-epimerase
IPR008183
Domain description: Aldose 1-/Glucose-6-phosphate 1-epimerase
Occurring in:
  1. Aldose 1-epimerase
IPR013458
Domain description: Aldose 1-epimerase, bacterial
Occurring in:
  1. Aldose 1-epimerase
IPR011013
Domain description: Galactose mutarotase-like domain superfamily
Occurring in:
  1. Aldose 1-epimerase
IPR015443
Domain description: Aldose 1-epimerase
Occurring in:
  1. Aldose 1-epimerase
IPR014718
Domain description: Glycoside hydrolase-type carbohydrate-binding
Occurring in:
  1. Aldose 1-epimerase

Structure domain

CATH CATH domain
2.70.98.10
Class: Mainly Beta
Architecture: Distorted Sandwich
Topology: Beta-galactosidase; Chain A, domain 5
Homology: Beta-galactosidase; Chain A, domain 5
Occurring in:
  1. Aldose 1-epimerase
The deposited structure of PDB entry 1ns0 contains 2 copies of CATH domain 2.70.98.10 (Beta-galactosidase; Chain A, domain 5) in Aldose 1-epimerase. Showing 1 copy in chain B.
SCOP SCOP annotation
74911
Class: All beta proteins
Fold: Supersandwich
Superfamily: Galactose mutarotase-like
Occurring in:
  1. Aldose 1-epimerase
The deposited structure of PDB entry 1ns0 contains 2 copies of SCOP domain 74911 (Aldose 1-epimerase (mutarotase)) in Aldose 1-epimerase. Showing 1 copy in chain B.

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