PDBe 1nrv

X-ray diffraction
1.65Å resolution

Crystal structure of the SH2 domain of Grb10


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Growth factor receptor-bound protein 10 Chains: A, B
Molecule details ›
Chains: A, B
Length: 105 amino acids
Theoretical weight: 12.36 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
  • Best match: Q13322 (Residues: 487-591)
Gene names: GRB10, GRBIR, KIAA0207

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12C
Spacegroup: P21
Unit cell:
a: 28.82Å b: 49.04Å c: 79.61Å
α: 90° β: 96.62° γ: 90°
R R work R free
0.225 0.224 0.242
Expression system: Escherichia coli BL21