Function and Biology

APOLIPOPROTEIN E3 (APOE3)

Source organism: Homo sapiens
Biochemical function: lipid binding
Biological process: lipoprotein metabolic process
Cellular component: extracellular region

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF01442
Domain description: Apolipoprotein A1/A4/E domain
Occurring in:
  1. Apolipoprotein E
The deposited structure of PDB entry 1nfn contains 1 copy of Pfam domain PF01442 (Apolipoprotein A1/A4/E domain) in Apolipoprotein E. Showing 1 copy in chain A.

InterPro InterPro annotation
IPR000074
Domain description: Apolipoprotein A/E
Occurring in:
  1. Apolipoprotein E

Structure domain

CATH CATH domain
1.20.120.20
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Four Helix Bundle (Hemerythrin (Met), subunit A)
Homology: Apolipoprotein
Occurring in:
  1. Apolipoprotein E
The deposited structure of PDB entry 1nfn contains 1 copy of CATH domain 1.20.120.20 (Four Helix Bundle (Hemerythrin (Met), subunit A)) in Apolipoprotein E. Showing 1 copy in chain A.
SCOP SCOP annotation
47163
Class: All alpha proteins
Fold: Four-helical up-and-down bundle
Superfamily: Apolipoprotein
Occurring in:
  1. Apolipoprotein E
The deposited structure of PDB entry 1nfn contains 1 copy of SCOP domain 47163 (Apolipoprotein) in Apolipoprotein E. Showing 1 copy in chain A.