PDBe 1ndi

X-ray diffraction
2.3Å resolution

Carnitine Acetyltransferase in complex with CoA

Released:

Function and Biology Details

Reaction catalysed:
Acetyl-CoA + carnitine = CoA + O-acetylcarnitine. 
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Carnitine O-acetyltransferase Chains: A, B
Molecule details ›
Chains: A, B
Length: 596 amino acids
Theoretical weight: 67.68 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P47934 (Residues: 30-625; Coverage: 95%)
Gene name: Crat
Sequence domains: Choline/Carnitine o-acyltransferase

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A
Spacegroup: C2
Unit cell:
a: 162.26Å b: 92.05Å c: 122.9Å
α: 90° β: 128.98° γ: 90°
R-values:
R R work R free
0.27 0.27 0.363
Expression system: Escherichia coli