PDBe 1nax

X-ray diffraction
2.7Å resolution

Thyroid receptor beta1 in complex with a beta-selective ligand

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thyroid hormone receptor beta Chain: A
Molecule details ›
Chain: A
Length: 252 amino acids
Theoretical weight: 28.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P10828 (Residues: 209-460; Coverage: 55%)
Gene names: ERBA2, NR1A2, THR1, THRB
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: C2221
Unit cell:
a: 76.52Å b: 107.743Å c: 66.896Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.196 0.196 0.237
Expression system: Escherichia coli BL21(DE3)