PDBe 1na7

X-ray diffraction
2.4Å resolution

Crystal structure of the catalytic subunit of human protein kinase CK2

Source organism: Homo sapiens
Primary publication:
Three-dimensional atomic structure of a catalytic subunit mutant of human protein kinase CK2.
Acta Crystallogr. D Biol. Crystallogr. 59 2133-9 (2003)
PMID: 14646071

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Casein kinase II subunit alpha Chain: A
Molecule details ›
Chain: A
Length: 329 amino acids
Theoretical weight: 39.33 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
  • Canonical: P68400 (Residues: 1-329; Coverage: 84%)
  • Best match: P68400-2 (Residues: 1-193)
Gene names: CK2A1, CSNK2A1
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID13
Spacegroup: P21
Unit cell:
a: 58.676Å b: 45.954Å c: 63.956Å
α: 90° β: 111.82° γ: 90°
R R work R free
0.215 0.209 0.273
Expression system: Escherichia coli BL21