PDBe 1n8y

X-ray diffraction
2.4Å resolution

Crystal structure of the extracellular region of rat HER2


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Receptor tyrosine-protein kinase erbB-2 Chain: C
Molecule details ›
Chain: C
Length: 608 amino acids
Theoretical weight: 67.36 KDa
Source organism: Rattus norvegicus
Expression system: Cricetulus griseus
  • Canonical: P06494 (Residues: 23-631; Coverage: 49%)
Gene names: Erbb2, Neu
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A
Spacegroup: P21212
Unit cell:
a: 130.87Å b: 116.4Å c: 55.37Å
α: 90° β: 90° γ: 90°
R R work R free
0.227 0.224 0.282
Expression system: Cricetulus griseus