PDBe 1n83

X-ray diffraction
1.63Å resolution

Crystal Structure of the complex between the Orphan Nuclear Hormone Receptor ROR(alpha)-LBD and Cholesterol


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Nuclear receptor ROR-alpha Chain: A
Molecule details ›
Chain: A
Length: 270 amino acids
Theoretical weight: 31.51 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
  • Canonical: P35398 (Residues: 271-523; Coverage: 48%)
Gene names: NR1F1, RORA, RZRA
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM1A
Spacegroup: P21
Unit cell:
a: 54.8Å b: 49.7Å c: 60.5Å
α: 90° β: 98.4° γ: 90°
R R work R free
0.202 0.201 0.223
Expression system: Spodoptera frugiperda