PDBe 1n5g

Solution NMR

NMR Structures of the Zinc Finger Domain of Human DNA Polymerase-alpha

Released:
Source organism: Homo sapiens

Function and Biology Details

Reaction catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA polymerase alpha catalytic subunit Chain: A
Molecule details ›
Chain: A
Length: 38 amino acids
Theoretical weight: 4.4 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P09884 (Residues: 1345-1382; Coverage: 3%)
Gene names: POLA, POLA1

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing and constrained molecular dynamics simulations
Expression system: Not provided