1mxh

X-ray diffraction
2.2Å resolution

Crystal Structure of Substrate Complex of Putative Pteridine Reductase 2 (PTR2) from Trypanosoma cruzi

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
PDBe Complex ID:
PDB-CPX-184720 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Putative pteridine reductase 2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 276 amino acids
Theoretical weight: 29.18 KDa
Source organism: Trypanosoma cruzi
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8I814 (Residues: 1-276; Coverage: 100%)
Gene name: ptr2
Sequence domains: Enoyl-(Acyl carrier protein) reductase
Structure domains: NAD(P)-binding Rossmann-like Domain

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P31
Unit cell:
a: 74.61Å b: 74.61Å c: 181.26Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.205 0.205 0.251
Expression system: Escherichia coli