PDBe 1mx4

X-ray diffraction
2Å resolution

Structure of p18INK4c (F82Q)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cyclin-dependent kinase 4 inhibitor C Chains: A, B
Molecule details ›
Chains: A, B
Length: 168 amino acids
Theoretical weight: 18.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P42773 (Residues: 1-168; Coverage: 100%)
Gene names: CDKN2C, CDKN6
Sequence domains: Ankyrin repeats (many copies)
Structure domains: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P21212
Unit cell:
a: 55.07Å b: 151.174Å c: 40.149Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.237 0.231 0.26
Expression system: Escherichia coli BL21(DE3)