PDBe 1mx2

X-ray diffraction
2.25Å resolution

Structure of F71N mutant of p18INK4c


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Cyclin-dependent kinase 4 inhibitor C Chains: A, B
Molecule details ›
Chains: A, B
Length: 168 amino acids
Theoretical weight: 18.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P42773 (Residues: 1-168; Coverage: 100%)
Gene names: CDKN2C, CDKN6
Sequence domains: Ankyrin repeats (many copies)
Structure domains: Ankyrin repeat-containing domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P21212
Unit cell:
a: 55.344Å b: 151.115Å c: 40.571Å
α: 90° β: 90° γ: 90°
R R work R free
0.218 0.214 0.254
Expression system: Escherichia coli