PDBe 1mwn

Solution NMR

Solution NMR structure of S100B bound to the high-affinity target peptide TRTK-12


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Protein S100-B Chains: A, B
Molecule details ›
Chains: A, B
Length: 92 amino acids
Theoretical weight: 10.76 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
  • Canonical: P04631 (Residues: 1-92; Coverage: 100%)
Gene name: S100b
Sequence domains:
Structure domains: EF-hand
F-actin-capping protein subunit alpha-1 Chains: X, Y
Molecule details ›
Chains: X, Y
Length: 12 amino acids
Theoretical weight: 1.48 KDa
Source organism: Homo sapiens
Expression system: Not provided
  • Canonical: P52907 (Residues: 265-276; Coverage: 4%)
Gene name: CAPZA1

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 82%
Refinement method: distance geometry, simulated annealing
Chemical shifts: BMR5544  
Expression systems:
  • Escherichia coli
  • Not provided