PDBe 1mri

X-ray diffraction
2.2Å resolution

STUDIES ON CRYSTAL STRUCTURES ACTIVE CENTER GEOMETRY AND DEPURINE MECHANISM OF TWO RIBOSOME-INACTIVATING PROTEINS

Released:

Function and Biology Details

Reaction catalysed:
Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA.
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ribosome-inactivating protein momordin I Chain: A
Molecule details ›
Chain: A
Length: 263 amino acids
Theoretical weight: 29.12 KDa
Source organism: Momordica charantia
Expression system: Not provided
UniProt:
  • Canonical: P16094 (Residues: 24-286; Coverage: 100%)
Sequence domains: Ribosome inactivating protein
Structure domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: R3
Unit cell:
a: 130.97Å b: 130.97Å c: 40.14Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.192 0.192 not available
Expression system: Not provided