› 1mqn

X-ray diffraction
3.2Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assemblies composition:
hetero hexamer (preferred)
hetero dodecamer
Assembly name:
PDBe Complex ID:
PDB-CPX-137034 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (5 distinct):
Hemagglutinin HA1 chain Chains: A, D, G
Molecule details ›
Chains: A, D, G
Length: 329 amino acids
Theoretical weight: 36.29 KDa
Source organism: Influenza A virus
UniProt:
  • Canonical: P03442 (Residues: 17-345; Coverage: 60%)
Gene name: HA
Sequence domains: Haemagglutinin
Structure domains: Hemagglutinin (Ha1 Chain); Chain: A; domain 1
Hemagglutinin HA2 chain Chains: B, E, H
Molecule details ›
Chains: B, E, H
Length: 221 amino acids
Theoretical weight: 25.57 KDa
Source organism: Influenza A virus
UniProt:
  • Canonical: P03442 (Residues: 346-566; Coverage: 40%)
Gene name: HA
Sequence domains: Haemagglutinin
Structure domains: Hemagglutinin Ectodomain; Chain B

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
Carbohydrate polymer : NEW Components: GAL, SIA
Carbohydrate polymer
1 bound ligand:
Ligand NAG 9 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 14-BM-C
Spacegroup: C2221
Unit cell:
a: 147.322Å b: 148.432Å c: 250.248Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.239 0.239 0.243

Quick links

Citations

20 review citations

Cross-species virus transmission and the emergence of new epidemic diseases.
Parrish et al. (2008)
19 more

18 mentions without citation

Structural insights into key sites of vulnerability on HIV-1 Env and influenza HA.
Julien et al. (2012)
17 more