PDBe 1md4

X-ray diffraction
2.1Å resolution

A folding mutant of human class pi glutathione transferase, created by mutating glycine 146 of the wild-type protein to valine

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutathione S-transferase P Chains: A, B
Molecule details ›
Chains: A, B
Length: 209 amino acids
Theoretical weight: 23.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P09211 (Residues: 2-210; Coverage: 100%)
Gene names: FAEES3, GST3, GSTP1
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: C2
Unit cell:
a: 77.27Å b: 89.44Å c: 68.92Å
α: 90° β: 98.07° γ: 90°
R-values:
R R work R free
0.207 0.207 0.235
Expression system: Escherichia coli