Function and Biology

Crystal Structure Of Phosphorylation-Mimicking Mutant T356D Of Annexin VI

Source organism: Homo sapiens
Biochemical function: calcium-dependent protein binding
Biological process: apoptotic signaling pathway
Cellular component: extracellular exosome

Sequence family

Pfam Protein family (Pfam)
PF00191
Domain description: Annexin
Occurring in:
  1. Annexin A6
The deposited structure of PDB entry 1m9i contains 8 copies of Pfam domain PF00191 (Annexin) in Annexin A6. Showing 8 copies in chain A.

InterPro InterPro annotations
IPR018502
Domain description: Annexin repeat
Occurring in:
  1. Annexin A6
IPR037104
Domain description: Annexin superfamily
Occurring in:
  1. Annexin A6
IPR018252
Domain description: Annexin repeat, conserved site
Occurring in:
  1. Annexin A6
IPR001464
Domain description: Annexin
Occurring in:
  1. Annexin A6
IPR002393
Domain description: Annexin A6
Occurring in:
  1. Annexin A6

Structure domain

CATH CATH domain
1.10.220.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Annexin V; domain 1
Homology: Annexin
Occurring in:
  1. Annexin A6
The deposited structure of PDB entry 1m9i contains 8 copies of CATH domain 1.10.220.10 (Annexin V; domain 1) in Annexin A6. Showing 8 copies in chain A.
SCOP SCOP annotation
47875
Class: All alpha proteins
Fold: Annexin
Superfamily: Annexin
Occurring in:
  1. Annexin A6
The deposited structure of PDB entry 1m9i contains 2 copies of SCOP domain 47875 (Annexin) in Annexin A6. Showing 2 copies in chain A.