PDBe 1m7n

X-ray diffraction
2.7Å resolution

Crystal Structure of Unactivated APO Insulin-like Growth Factor-1 Receptor Kinase Domain


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Insulin-like growth factor 1 receptor beta chain Chains: A, B
Molecule details ›
Chains: A, B
Length: 322 amino acids
Theoretical weight: 36.77 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
  • Canonical: P08069 (Residues: 974-1294; Coverage: 24%)
Gene name: IGF1R
Sequence domains: Protein tyrosine kinase
Structure domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P21
Unit cell:
a: 52.88Å b: 78.06Å c: 78.97Å
α: 90° β: 99.17° γ: 90°
R R work R free
0.229 0.229 0.294
Expression system: Spodoptera frugiperda