PDBe 1m6k

X-ray diffraction
1.5Å resolution

Structure of the OXA-1 class D beta-lactamase

Released:

Function and Biology Details

Reaction catalysed:
A beta-lactam + H(2)O = a substituted beta-amino acid. 
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Beta-lactamase OXA-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 251 amino acids
Theoretical weight: 28.2 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P13661 (Residues: 26-276; Coverage: 100%)
Gene names: bla, oxa1
Sequence domains: Penicillin binding protein transpeptidase domain
Structure domains: DD-peptidase/beta-lactamase superfamily

Ligands and Environments

1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: P1
Unit cell:
a: 36.02Å b: 51.62Å c: 72.89Å
α: 70.19° β: 84.11° γ: 81.51°
R-values:
R R work R free
0.182 0.182 0.203
Expression system: Escherichia coli BL21