PDBe 1m52

X-ray diffraction
2.6Å resolution

Crystal Structure of the c-Abl Kinase domain in complex with PD173955

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tyrosine-protein kinase ABL1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 293 amino acids
Theoretical weight: 33.74 KDa
Source organism: Mus musculus
Expression system: Spodoptera frugiperda
UniProt:
  • Best match: P00520 (Residues: 229-515)
Gene names: Abl, Abl1

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P21212
Unit cell:
a: 115.848Å b: 125.708Å c: 56.718Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.211 0.211 0.254
Expression system: Spodoptera frugiperda