PDBe 1m14

X-ray diffraction
2.6Å resolution

Tyrosine Kinase Domain from Epidermal Growth Factor Receptor

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Epidermal growth factor receptor Chain: A
Molecule details ›
Chain: A
Length: 333 amino acids
Theoretical weight: 37.88 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Best match: P00533 (Residues: 695-1022)
Gene names: EGFR, ERBB, ERBB1, HER1

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: I23
Unit cell:
a: 146.8Å b: 146.8Å c: 146.8Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.24 0.238 0.286
Expression system: Spodoptera frugiperda