PDBe 1m10

X-ray diffraction
3.1Å resolution

Crystal structure of the complex of Glycoprotein Ib alpha and the von Willebrand Factor A1 Domain

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Glycocalicin Chain: B
Molecule details ›
Chain: B
Length: 290 amino acids
Theoretical weight: 32.33 KDa
Source organism: Homo sapiens
Expression system: Mesocricetus auratus
UniProt:
  • Canonical: P07359 (Residues: 17-306; Coverage: 46%)
Gene name: GP1BA
Sequence domains:
Structure domains: Ribonuclease Inhibitor
von Willebrand factor Chain: A
Molecule details ›
Chain: A
Length: 208 amino acids
Theoretical weight: 23.73 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
  • Canonical: P04275 (Residues: 1261-1468; Coverage: 8%)
Gene names: F8VWF, VWF
Sequence domains: von Willebrand factor type A domain
Structure domains: Rossmann fold

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: P61
Unit cell:
a: 89.84Å b: 89.84Å c: 124.63Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.237 0.234 0.296
Expression systems:
  • Mesocricetus auratus
  • Komagataella pastoris