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CRYSTAL STRUCTURE OF FXA IN COMPLEX WITH 79.

X-ray diffraction
2Å resolution
PDB entry 1lpg coloured by chain, front view.
PDB entry 1lpg coloured by chain, side view.
PDB entry 1lpg coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 2 distinct polypeptide molecules

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Assemblies

Assembly 1
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Assembly Name: Activated factor Xa heavy chain
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Multimeric state: monomeric
PDBe Complex ID: PDB-CPX-133208
Assembly 2 (preferred)
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Assembly Name: Activated factor Xa heavy chain
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Multimeric state: monomeric
PDBe Complex ID: PDB-CPX-133208

Macromolecules

Factor X light chain
Chain: A
Length: 134 amino acids
Theoretical weight: 15.21 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P00742 (Residues: 46-179; Coverage: 29%)
Gene name: F10
Pfam:
InterPro:
CATH: Laminin
SCOP: EGF-type module
Factor X light chain in PDB entry 1lpg, assembly 1, front view.
Factor X light chain in PDB entry 1lpg, assembly 1, side view.
Factor X light chain in PDB entry 1lpg, assembly 1, top view.
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Activated factor Xa heavy chain
Chain: B
Length: 254 amino acids
Theoretical weight: 28.55 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P00742 (Residues: 235-488; Coverage: 56%)
Gene name: F10
Pfam: Trypsin
InterPro:
CATH: Trypsin-like serine proteases
SCOP: Eukaryotic proteases
Activated factor Xa heavy chain in PDB entry 1lpg, assembly 2, front view.
Activated factor Xa heavy chain in PDB entry 1lpg, assembly 2, side view.
Activated factor Xa heavy chain in PDB entry 1lpg, assembly 2, top view.
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