PDBe 1lp8

X-ray diffraction
1.65Å resolution

HIGH RESOLUTION STRUCTURE OF RECOMBINANT DIANTHIN ANTIVIRAL PROTEIN-POTENT ANTI-HIV AGENT

Released:

Function and Biology Details

Reaction catalysed:
Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA.
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Antiviral protein DAP-30 Chain: A
Molecule details ›
Chain: A
Length: 254 amino acids
Theoretical weight: 28.6 KDa
Source organism: Dianthus caryophyllus
Expression system: Escherichia coli
UniProt:
  • Canonical: P24476 (Residues: 24-277; Coverage: 94%)
Sequence domains: Ribosome inactivating protein
Structure domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P21
Unit cell:
a: 37.071Å b: 78.559Å c: 42.674Å
α: 90° β: 105.301° γ: 90°
R-values:
R R work R free
0.186 0.18 0.23
Expression system: Escherichia coli