PDBe 1lij

X-ray diffraction
1.86Å resolution

STRUCTURE OF T. GONDII ADENOSINE KINASE BOUND TO PRODRUG 2 7-IODOTUBERCIDIN AND AMP-PCP

Released:

Function and Biology Details

Reaction catalysed:
ATP + adenosine = ADP + AMP. 
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adenosine kinase Chain: A
Molecule details ›
Chain: A
Length: 363 amino acids
Theoretical weight: 38.37 KDa
Source organism: Toxoplasma gondii
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9TVW2 (Residues: 1-363; Coverage: 100%)
Gene name: AK
Sequence domains: pfkB family carbohydrate kinase
Structure domains:

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: P21212
Unit cell:
a: 167.7Å b: 46.97Å c: 44.09Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.185 0.185 0.239
Expression system: Escherichia coli