PDBe 1lgb

X-ray diffraction
3.3Å resolution

INTERACTION OF A LEGUME LECTIN WITH THE N2 FRAGMENT OF HUMAN LACTOTRANSFERRIN OR WITH THE ISOLATED BIANTENNARY GLYCOPEPTIDE: ROLE OF THE FUCOSE MOIETY

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero hexamer
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Lactotransferrin Chain: C
Molecule details ›
Chain: C
Length: 159 amino acids
Theoretical weight: 17.54 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P02788 (Residues: 110-268; Coverage: 23%)
Gene names: GIG12, LF, LTF
Structure domains: Periplasmic binding protein-like II
Mannose/glucose-specific lectin alpha 2 chain Chain: B
Molecule details ›
Chain: B
Length: 53 amino acids
Theoretical weight: 5.92 KDa
Source organism: Lathyrus ochrus
UniProt:
  • Canonical: P12307 (Residues: 1-53; Coverage: 100%)
Sequence domains: Legume lectin domain
Lectin beta-1 and beta-2 chains Chain: A
Molecule details ›
Chain: A
Length: 181 amino acids
Theoretical weight: 19.8 KDa
Source organism: Lathyrus ochrus
UniProt:
  • Canonical: P04122 (Residues: 1-181; Coverage: 100%)
Sequence domains: Legume lectin domain
Structure domains: Jelly Rolls

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P43212
Unit cell:
a: 63.5Å b: 63.5Å c: 251.9Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.21 0.21 not available