Function and Biology

NMR Solution Structure of the Extended PBX Homeodomain Bound to DNA

Source organism: Mus musculus
Biochemical function: DNA binding
Biological process: regulation of DNA-templated transcription
Cellular component: not assigned

GO terms

Sequence family

Pfam Protein family (Pfam)
PF05920
Domain description: Homeobox KN domain
Occurring in:
  1. Pre-B-cell leukemia transcription factor 1

InterPro InterPro annotations
IPR001356
Domain description: Homeobox domain
Occurring in:
  1. Pre-B-cell leukemia transcription factor 1
IPR017970
Domain description: Homeobox, conserved site
Occurring in:
  1. Pre-B-cell leukemia transcription factor 1
IPR009057
Domain description: Homeobox-like domain superfamily
Occurring in:
  1. Pre-B-cell leukemia transcription factor 1

Structure domain

CATH CATH domain
1.10.10.60
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Arc Repressor Mutant, subunit A
Homology: Homeodomain-like
Occurring in:
  1. Pre-B-cell leukemia transcription factor 1
The deposited structure of PDB entry 1lfu contains 1 copy of CATH domain 1.10.10.60 (Arc Repressor Mutant, subunit A) in Pre-B-cell leukemia transcription factor 1. Showing 1 copy in chain C [auth P].
SCOP SCOP annotation
46690
Class: All alpha proteins
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: Homeodomain-like
Occurring in:
  1. Pre-B-cell leukemia transcription factor 1
The deposited structure of PDB entry 1lfu contains 1 copy of SCOP domain 46690 (Homeodomain) in Pre-B-cell leukemia transcription factor 1. Showing 1 copy in chain C [auth P].