PDBe 1lc3

X-ray diffraction
1.5Å resolution

Crystal Structure of a Biliverdin Reductase Enzyme-Cofactor Complex

Released:
Source organism: Rattus norvegicus

Function and Biology Details

Reaction catalysed:
Bilirubin + NAD(P)(+) = biliverdin + NAD(P)H
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Biliverdin reductase A Chain: A
Molecule details ›
Chain: A
Length: 294 amino acids
Theoretical weight: 33.39 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P46844 (Residues: 8-295; Coverage: 98%)
Gene names: Blvr, Blvra
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand NAD 2 x NAD
1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P212121
Unit cell:
a: 51.78Å b: 76.14Å c: 75.01Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.214 0.214 0.234
Expression system: Escherichia coli