PDBe 1l0x

X-ray diffraction
2.8Å resolution

TCR beta chain complexed with streptococcal superantigen SpeA

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Exotoxin type A Chains: B, D
Molecule details ›
Chains: B, D
Length: 221 amino acids
Theoretical weight: 25.8 KDa
Source organism: Streptococcus pyogenes
Expression system: Escherichia coli
UniProt:
  • Canonical: P0DJY7 (Residues: 34-169, 170-250; Coverage: 99%)
Gene name: speA
Sequence domains:
Structure domains:
T-cell receptor beta-2 chain C region Chains: A, C
Molecule details ›
Chains: A, C
Length: 238 amino acids
Theoretical weight: 26.57 KDa
Source organism: Mus musculus
Expression system: Mus musculus
UniProt:
  • Canonical: P01851 (Residues: 1-126; Coverage: 73%)
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P21
Unit cell:
a: 71.4Å b: 83.25Å c: 93.583Å
α: 90° β: 91.63° γ: 90°
R-values:
R R work R free
0.232 0.232 0.278
Expression systems:
  • Escherichia coli
  • Mus musculus