› 1ky3

X-ray diffraction
1.35Å resolution

GDP-BOUND YPT7P AT 1.35 A RESOLUTION

Released:
DOI: 10.2210/pdb1ky3/pdb
PDB entry 1ky3 coloured by chain, front view.
PDB entry 1ky3 coloured by chain, side view.
PDB entry 1ky3 coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Rab-subfamily-specific regions of Ypt7p are structurally different from other RabGTPases.
Constantinescu AT, Rak A, Alexandrov K, Esters H, Goody RS, Scheidig AJ
Structure 10 569-79 (2002)
PMID: 11937061

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152517 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ypt/Rab-type GTPase YPT7 Chain: A
Molecule details ›
Chain: A
Length: 182 amino acids
Theoretical weight: 20.16 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P32939 (Residues: 1-182; Coverage: 88%)
Gene names: VAM4, YM8270.02, YML001W, YPT7
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

2 bound ligands:
Ligand MG 1 x MG
Ligand GDP 1 x GDP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P212121
Unit cell:
a: 49.535Å b: 55.43Å c: 60.177Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.191 0.161 0.227
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 review citations

Structural clues to Rab GTPase functional diversity.
Pfeffer SR. (2005)
2 more

9 mentions without citation

Structural mechanisms for regulation of membrane traffic by rab GTPases.
Lee et al. (2009)
8 more