PDBe 1kwp

X-ray diffraction
2.8Å resolution

Function and Biology Details

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo hexamer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
MAP kinase-activated protein kinase 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 400 amino acids
Theoretical weight: 45.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P49137 (Residues: 1-400; Coverage: 100%)
Gene name: MAPKAPK2
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: R3
Unit cell:
a: 143.944Å b: 143.944Å c: 90.273Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.233 0.233 0.245
Expression system: Escherichia coli