PDBe 1kwa

X-ray diffraction
1.93Å resolution

HUMAN CASK/LIN-2 PDZ DOMAIN

Released:

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein. 
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo tetramer
homo dimer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peripheral plasma membrane protein CASK Chains: A, B
Molecule details ›
Chains: A, B
Length: 88 amino acids
Theoretical weight: 10.19 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O14936 (Residues: 487-572; Coverage: 9%)
Gene names: CASK, LIN2
Sequence domains: PDZ domain (Also known as DHR or GLGF)
Structure domains: Pdz3 Domain

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL1-5
Spacegroup: C2221
Unit cell:
a: 40.8Å b: 97Å c: 92Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.251 0.251 0.298
Expression system: Escherichia coli