PDBe 1ksw

X-ray diffraction
2.8Å resolution

Structure of Human c-Src Tyrosine Kinase (Thr338Gly Mutant) in Complex with N6-benzyl ADP

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Proto-oncogene tyrosine-protein kinase Src Chain: A
Molecule details ›
Chain: A
Length: 452 amino acids
Theoretical weight: 51.67 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Best match: P12931 (Residues: 86-536)
Gene names: SRC, SRC1

Ligands and Environments

1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: P212121
Unit cell:
a: 50.81Å b: 87.68Å c: 106.28Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.231 0.231 0.294
Expression system: Spodoptera frugiperda