Structure analysis

structure of the triple (Lys(beta)D3Ala, Asp(beta)C8Ala, AspCD2Ala) mutant of the Src SH2 domain bound to the PQpYEEIPI peptide

X-ray diffraction
2.1Å resolution
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules


Assembly 1 (preferred)
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Multimeric state: hetero dimer

Binding statistics and energies are not available for this assembly


Chain: B
Length: 8 amino acids
Theoretical weight: 1.07 KDa
Source organism: Synthetic construct
Expression system: Not provided

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Chain: A
Length: 103 amino acids
Theoretical weight: 11.7 KDa
Source organism: Rous sarcoma virus
Expression system: Escherichia coli
  • Canonical: P00524 (Residues: 145-247; Coverage: 20%)
Gene name: V-SRC
Pfam: SH2 domain
CATH: SHC Adaptor Protein
SCOP: SH2 domain

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