PDBe 1ka7

Solution NMR

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Signaling lymphocytic activation molecule Chain: B
Molecule details ›
Chain: B
Length: 12 amino acids
Theoretical weight: 1.44 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q13291 (Residues: 276-286; Coverage: 4%)
Gene names: SLAM, SLAMF1
SH2 domain-containing protein 1A Chain: A
Molecule details ›
Chain: A
Length: 128 amino acids
Theoretical weight: 14.21 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O60880 (Residues: 1-128; Coverage: 100%)
Gene names: DSHP, SAP, SH2D1A
Sequence domains: SH2 domain
Structure domains: SHC Adaptor Protein

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 84%
Refinement method: simulated annealing
Chemical shifts: BMR5211  
Expression systems:
  • Not provided
  • Escherichia coli BL21(DE3)