PDBe 1k4u

Solution NMR

Solution structure of the C-terminal SH3 domain of p67phox complexed with the C-terminal tail region of p47phox

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Neutrophil cytosol factor 1 Chain: P
Molecule details ›
Chain: P
Length: 32 amino acids
Theoretical weight: 3.42 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P14598 (Residues: 359-390; Coverage: 8%)
Gene names: NCF1, NOXO2, SH3PXD1A
Neutrophil cytosol factor 2 Chain: S
Molecule details ›
Chain: S
Length: 62 amino acids
Theoretical weight: 6.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P19878 (Residues: 455-516; Coverage: 12%)
  • Best match: P19878-2 (Residues: 374-420)
Gene names: NCF2, NOXA2, P67PHOX
Sequence domains: SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 89%
Refinement method: simulated annealing
Chemical shifts: BMR5498  
Expression system: Escherichia coli BL21(DE3)