Function and Biology

Potassium Channel KcsA-Fab complex in high concentration of K+

GO terms

Sequence family

Pfam Protein family (Pfam)
PF07885
Domain description: Ion channel
Occurring in:
  1. pH-gated potassium channel KcsA
1 copy of Pfam domain PF07885 (Ion channel) in pH-gated potassium channel KcsA in PDB 1k4c.

InterPro InterPro annotations
IPR036179
Domain description: Immunoglobulin-like domain superfamily
Occurring in:
  1. antibody Fab fragment heavy chain
  2. antibody Fab fragment light chain
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. antibody Fab fragment heavy chain
  2. antibody Fab fragment light chain
IPR003597
Domain description: Immunoglobulin C1-set
Occurring in:
  1. antibody Fab fragment heavy chain
  2. antibody Fab fragment light chain
IPR013106
Domain description: Immunoglobulin V-set domain
Occurring in:
  1. antibody Fab fragment heavy chain
  2. antibody Fab fragment light chain
IPR007110
Domain description: Immunoglobulin-like domain
Occurring in:
  1. antibody Fab fragment heavy chain
  2. antibody Fab fragment light chain
IPR028325
Domain description: Voltage-gated potassium channel
Occurring in:
  1. pH-gated potassium channel KcsA
IPR003599
Domain description: Immunoglobulin subtype
Occurring in:
  1. antibody Fab fragment heavy chain
  2. antibody Fab fragment light chain
IPR013099
Domain description: Potassium channel domain
Occurring in:
  1. pH-gated potassium channel KcsA
IPR003006
Domain description: Immunoglobulin/major histocompatibility complex, conserved site
Occurring in:
  1. antibody Fab fragment light chain
IPR003598
Domain description: Immunoglobulin subtype 2
Occurring in:
  1. antibody Fab fragment light chain

Structure domains

CATH CATH domains
2.60.40.10
Class: Mainly Beta
Architecture: Sandwich
Topology: Immunoglobulin-like
Homology: Immunoglobulins
Occurring in:
  1. antibody Fab fragment heavy chain
  2. antibody Fab fragment light chain
4 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in antibody Fab fragment light chain in PDB 1k4c.
2 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in antibody Fab fragment heavy chain in PDB 1k4c.
1.10.287.70
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Helix Hairpins
Homology: Helix Hairpins
Occurring in:
  1. pH-gated potassium channel KcsA
1 copy of CATH domain 1.10.287.70 (Helix Hairpins) in pH-gated potassium channel KcsA in PDB 1k4c.
SCOP SCOP annotations
48942
Class: All beta proteins
Fold: Immunoglobulin-like beta-sandwich
Superfamily: Immunoglobulin
Occurring in:
  1. antibody Fab fragment heavy chain
  2. antibody Fab fragment light chain
2 copies of SCOP domain 48942 (C1 set domains (antibody constant domain-like)) in antibody Fab fragment light chain in PDB 1k4c.
1 copy of SCOP domain 48942 (C1 set domains (antibody constant domain-like)) in antibody Fab fragment heavy chain in PDB 1k4c.
48727
Class: All beta proteins
Fold: Immunoglobulin-like beta-sandwich
Superfamily: Immunoglobulin
Occurring in:
  1. antibody Fab fragment heavy chain
  2. antibody Fab fragment light chain
2 copies of SCOP domain 48727 (V set domains (antibody variable domain-like)) in antibody Fab fragment light chain in PDB 1k4c.
1 copy of SCOP domain 48727 (V set domains (antibody variable domain-like)) in antibody Fab fragment heavy chain in PDB 1k4c.
81323
Class: Membrane and cell surface proteins and peptides
Fold: Voltage-gated potassium channels
Superfamily: Voltage-gated potassium channels
Occurring in:
  1. pH-gated potassium channel KcsA
1 copy of SCOP domain 81323 (Voltage-gated potassium channels) in pH-gated potassium channel KcsA in PDB 1k4c.