PDBe 1k25

X-ray diffraction
3.2Å resolution

PBP2x from a Highly Penicillin-resistant Streptococcus pneumoniae Clinical Isolate

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Low-affinity penicillin-binding protein 2X Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 685 amino acids
Theoretical weight: 75.26 KDa
Source organism: Streptococcus pneumoniae
Expression system: Escherichia coli
UniProt:
  • Canonical: O34006 (Residues: 66-750; Coverage: 91%)
Gene name: pbp2X
Sequence domains:
Structure domains: DD-peptidase/beta-lactamase superfamily

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P32
Unit cell:
a: 146.56Å b: 146.56Å c: 132.61Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.235 0.235 0.312
Expression system: Escherichia coli