PDBe 1k0x

Solution NMR

Solution Structure of Melanoma Inhibitory Activity Protein

Released:
Source organism: Homo sapiens
Primary publication:
Solution structure and dynamics of melanoma inhibitory activity protein.
J. Biomol. NMR 22 211-23 (2002)
PMID: 11991352

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Melanoma-derived growth regulatory protein Chain: A
Molecule details ›
Chain: A
Length: 108 amino acids
Theoretical weight: 12.26 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q16674 (Residues: 25-131; Coverage: 100%)
Gene name: MIA
Sequence domains: Variant SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 84%
Refinement method: Restrained molecular dynamics-simulated annealing coupled with the ambiguous restraints for iterative assignment (ARIA) extension of Nilges (M. Nilges, J. Mol. Biol. 245, 645-660, 1995).
Chemical shifts: BMR5220  
Expression system: Escherichia coli